MICROFLUIDIC SYNTHESIS OF VINBLASTINE-LOADED MULTIFUNCTIONAL PARTICLES FOR MAGNETICALLY RESPONSIVE CONTROLLED DRUG RELEASE

Microfluidic Synthesis of Vinblastine-Loaded Multifunctional Particles for Magnetically Responsive Controlled Drug Release

Vinblastine (VBL) is a major chemotherapeutic drug; however, in some cases, it may cause severe side effects in patients with cancer.Designing a novel VBL pharmaceutical formulation is a crucial and emerging concern among researchers for reducing the use of VBL.This study developed a stimuli-responsive controlled VBL drug release system from magnet

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Spatiotemporal differentiation and driving mechanisms of high-level Grade A tourist attractions in the Yangtze River Delta City Cluster.

Herein, the spatial evolution characteristics of high-level Grade A tourist attractions in the Yangtze River Delta (YRD) urban agglomeration, from 2001 to 2021, are studied by comprehensively applying the nearest neighbor index, kernel density analysis, standard deviation ellipse, and spatial autocorrelation.High-level Grade A tourist attractions a

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Numerical Analysis of Friction-Filling Performance of Friction-Type Vertical Disc Precision Seed-Metering Device Based on EDEM

A seed-metering device is a key component for precision exfoliate seeding and the core component of precision seed-metering devices.Nowadays, high-speed seeding is a trend in the development of seed-metering devices, but the filling performance of mechanical seed-metering devices decreases under the condition of high speed.Therefore, this paper exp

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Purkinje Cell Activity in the Medial and Lateral Cerebellum During Suppression of Voluntary Eye Movements in Rhesus Macaques

Volitional suppression of responses to distracting external stimuli enables us to achieve our goals.This volitional inhibition of a specific behavior is supposed to be mainly mediated by the Pants cerebral cortex.However, recent evidence supports the involvement of the cerebellum in this process.It is currently not known whether different parts of

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